Practical Biostatistics in Translational Healthcare
By Allen M. Khakshooy, Francesco Chiappelli
Springer | July 2018 | ISBN-10: 3662574357 | ePUB/True PDF | 24/10 mb

There is an ever-increasing emphasis on evidence-based medicine that is distinguished by systematic crafting of the patient-centered research question, detailed literature searches, and careful appraisal of the resulting evidence. The consensus that ultimately emerges must then be applied in specific clinical settings, and it is to this process that translational effectiveness analysis refers. This portable and easy-to-use handbook is intended as a practical teaching guide on translational effectiveness for students and clinicians.
Specifically, it will serve as a primer on patient-centered outcomes research methodology in the health sciences and explain how to acquire and understand the fundamental data that determine which reports are valued as the "best available" evidence. It presents an accessible and readily intelligible set of principles which doctors, dentists, nurses, and insurance carriers will be able to use in the process of health care-related decision-making.

About the AuthorS
Allen M. Khakshooy, MPH MDc was recognized as the youngest appointed faculty member in his graduate department due to his comprehensive understanding and effective teaching of Biostatistics to future Healthcare professionals. Mr. Khakshooy is currently in pursuit of his medical doctorate. 
Professor Francesco Chiappelli, Ph.D. has contributed extensively to the development of the field of evidence-based and comparative effectiveness decision-making in health care over the past several years through his teaching, research publications, and authorship of several book chapters and books.

CONTENTS
Part I Fundamental Biostatistics for Translational Research
1 Introduction to Biostatistics.  . . . 3
2 Study Design.  . . . 13
3 Methodology .  . . . 27
4 Descriptive Statistics.  . . . 43
5 Inferential Statistics I.  . . . 71
6 Inferential Statistics II.  . . . 91
7 Nonparametric Statistics.  . . . 123
Part II Biostatistics for Translational Effectiveness
8 Individual Patient Data .  . . . 141
9 Evaluation.. . . 157
10 New Frontiers in Comparative Effectiveness Research. . . . 167
Appendices.  . . . 185
Appendix A: Random Number Table.  . . . 186
Appendix B: Standard Normal Distribution (z)  . . . 	188
Appendix C: Critical t Values.  . . . 190
Appendix D: Critical Values of F.  . . . 191
Appendix E: Sum of Squares (SS) Stepwise Calculation Method . . . . 194
Appendix F: Critical Values for Wilcoxon T  . . . 195
Appendix G: Critical Values for Mann-Whitney U  . . . 197
Appendix H: Critical Values for the Chi-Square Distribution. . . . 201
Answers to Chapter Practice Problems  . . . 203
Bibliography  . . . 215
Index.  . . . 221
 
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